Prevalence of methylenetetrahydrofolate reductase gene polymorphisms (C677T, and A1298C) among Saudi children receiving dental treatment
نویسندگان
چکیده
منابع مشابه
Association of Methylenetetrahydrofolate Reductase (MTHFR) Gene C677T and A1298C Polymorphisms with Myocardial Infarction From North of Fars Province
Background: The association between Methylene tetrahydrofolate reductase polymorphism and Coronary Artery diseases risk has been both confirmed and refuted in a number of published studies. The aim of this study was to investigate whether genetic polymorphisms of MTHFR (C677T, A1298C) contributed to the development of myocardial infarction (MI). Materials and Methods: The present case-contro...
متن کاملPrevalence of MTHFR gene polymorphisms (C677T and A1298C) among Tamilians.
We have investigated the incidence of the C677T and A1298C methylene tetrahydrofolate reductase (MTHFR) gene single nucleotide polymorphisms (SNPs) in the South Indian Tamil Nadu population with a total number of 72 individuals. The MTHFR genotyping was performed using the polymerase chain reaction followed by restriction enzyme analysis. Homozygosity for the MTHFR A1298C SNP was detected in 15...
متن کاملMethylenetetrahydrofolate reductase gene polymorphisms are associated with ischemic and hemorrhagic stroke: Dual effect of MTHFR polymorphisms C677T and A1298C.
Hyperhomocysteinemia is an independent risk factor for ischemic stroke. The enzyme methylenetetrahydrofolate reductase (MTHFR) plays a critical role in modulating the levels of plasma homocysteine. Two polymorphisms in the MTHFR gene, C677T, A1298C result in reduced enzyme activity. The mechanisms of ischemic and hemorrhagic stroke are not well understood. Although controversial, previous studi...
متن کاملMethylenetetrahydrofolate Reductase C677T and A1298C Polymorphisms in Male Partners of Recurrent Miscarriage Couples.
BACKGROUND Methylenetetrahydrofolate reductase (MTHFR) single-nucleotide polymorphisms (SNPs) C677T and A1298C have been described as strong risk factors for idiopathic recurrent miscarriage (RM). However, very few studies have investigated the association of paternal MTHFR SNPs with RM. The aim of the present study was to evaluate the prevalence of paternal C677T and A1298C SNPs among Iranian ...
متن کاملmethylenetetrahydrofolate reductase c677t and a1298c polymorphisms in male partners of recurrent miscarriage couples
background: methylenetetrahydrofolate reductase (mthfr) single-nucleotide polymorphisms (snps) c677t and a1298c have been described as strong risk factors for idiopathic recurrent miscarriage (rm). however, very few studies have investigated the association of paternal mthfr snps with rm. the aim of the present study was to evaluate the prevalence of paternal c677t and a1298c snps among iranian...
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ژورنال
عنوان ژورنال: Annals of Saudi Medicine
سال: 2021
ISSN: 0256-4947,0975-4466
DOI: 10.5144/0256-4947.2021.1